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Scientists developing female condom that’ll dissolve inside the body

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A team of scientists at the University Of Washington are developing a product that women can use to protect themselves from HIV infection and unintended pregnancy.

The only way to protect against HIV and unintended pregnancy today is the condom. It’s an effective technology, but not appropriate or popular in all situations.

A University of Washington team has developed a versatile platform to simultaneously offer contraception and prevent HIV. Electrically spun cloth with nanometer-sized fibers can dissolve to release drugs, providing a platform for cheap, discrete and reversible protection.

The research was published this week in the Public Library of Science’s open-access journal PLoS One. The Bill & Melinda Gates Foundation last month awarded the UW researchers almost $1 million to pursue the technology.

“Our dream is to create a product women can use to protect themselves from HIV infection and unintended pregnancy,” said corresponding author Kim Woodrow, a UW assistant professor of bioengineering. “We have the drugs to do that. It’s really about delivering them in a way that makes them more potent, and allows a woman to want to use it.”

Electrospinning uses an electric field to catapult a charged fluid jet through air to create very fine, nanometer-scale fibers. The fibers can be manipulated to control the material’s solubility, strength and even geometry. Because of this versatility, fibers may be better at delivering medicine than existing technologies such as gels, tablets or pills. No high temperatures are involved, so the method is suitable for heat-sensitive molecules. The fabric can also incorporate large molecules, such as proteins and antibodies, that are hard to deliver through other methods.

At a lab meeting last year, Woodrow presented the concept, and co-authors Emily Krogstad and Cameron Ball, both first-year graduate students, pursued the idea.

They first dissolved polymers approved by the Food and Drug Administration and antiretroviral drugs used to treat HIV to create a gooey solution that passes through a syringe. As the stream encounters the electric field it stretches to create thin fibers measuring 100 to several thousand nanometers that whip through the air and eventually stick to a collecting plate (one nanometer is about one 25-millionth of an inch). The final material is a stretchy fabric that can physically block sperm or release chemical contraceptives and antivirals.

fibers

“This method allows controlled release of multiple compounds,” Ball said. “We were able to tune the fibers to have different release properties.”

One of the fabrics they made dissolves within minutes, potentially offering users immediate, discrete protection against unwanted pregnancy and sexually transmitted diseases.

Another dissolves gradually over a few days, providing an option for sustained delivery, more like the birth-control pill, to provide contraception and guard against HIV.

The fabric could incorporate many fibers to guard against many different sexually transmitted infections, or include more than one anti-HIV drug to protect against drug-resistant strains (and discourage drug-resistant strains from emerging). Mixed fibers could be designed to release drugs at different times to increase their potency, like the prime-boost method used in vaccines.

The electrospun cloth could be inserted directly in the body or be used as a coating on vaginal rings or other products.

Electrospinning has existed for decades, but it’s only recently been automated to make it practical for applications such as filtration and tissue engineering. This is the first study to use nanofibers for vaginal drug delivery.

While this technology is more discrete than a condom, and potentially more versatile than pills or plastic or rubber devices, researchers say there is no single right answer.

“At the time of sex, are people going to actually use it? That’s where having multiple options really comes into play,” Krogstad said. “Depending on cultural background and personal preferences, certain populations may differ in terms of what form of technology makes the most sense for them.”

The team is focusing on places like Africa where HIV is most common, but the technology could be used in the U.S. or other countries to offer birth control while also preventing one or more sexually transmitted diseases.

The research to date was funded by the National Institutes of Health and the UW’s Center for AIDS Research. The other co-author on the paper is Thanyanan Chaowanachan, a UW postdoctoral researcher and longtime HIV expert.

The team will use the new Gates Foundation grant to evaluate the versatility and feasibility of their system. The group will hire more research staff and buy an electrospinning machine to make butcher-paper sized sheets. The expanded team will spend a year testing combinations that deliver two antiretroviral drugs used to treat HIV and a hormonal contraceptive, and then six months scaling up production of the most promising materials.

Source: News Release University of Washington

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Himachal Teen Survives 12-Minute Leopard Attack, Kills Predator in Self-Defense

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Solan—In a shocking incident on Monday, an 18-year-old youth, Pravesh, survived a vicious leopard attack in Sarli village of Arki subdivision. The teenager reportedly fought the leopard for nearly 12 minutes before breaking its jaw, killing the animal on the spot.

Quick Thinking Saved His Life

Pravesh told the media that he was walking from the fields to a nearby shop in the morning to fetch milk when the leopard, hidden in the crops, lunged at him. Noticing the leopard’s tail, he attempted to run but fell after a short distance. During the attack, he covered his neck with his hands to protect himself from fatal bites.

The teenager continued to struggle with the leopard, repeatedly attempting to put distance between himself and the predator. In a desperate move, he grabbed the leopard by its mouth, twisted its jaw, and broke it, killing the animal instantly. Pravesh sustained multiple injuries, including deep claw marks, and is currently receiving treatment at Arki Hospital. Police and forest department teams have launched an investigation into the incident.

Serious Allegations of HP Forest Department’s Negligence

One of Pravesh’s relatives accused the forest department of negligence, noting that similar attacks had occurred in the area previously.

Earlier, a leopard had attempted to attack a scooter rider, who managed to escape. The family said they had informed the forest department on March 6 about potential danger, but no concrete action was taken. Villagers waited for three hours for a forest team to arrive, but none came. When the Block Officer eventually visited, he reportedly told villagers to ensure their own safety. Requests for cages to capture the leopard were also denied, with officials asking for written complaints instead.

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Weather Forecast for Himachal Pradesh For the Next Two Weeks

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SHIMLA | 7 August 2025 –The India Meteorological Department (IMD) has forecast light to moderate rainfall across Himachal Pradesh over the next two weeks, with isolated heavy to very heavy showers likely over the low hills, plains, and adjoining mid-hill regions. While the ongoing monsoon remains vital for agriculture, it also brings an elevated risk of localized flooding and landslides.

Week of August 8–14

Maximum temperatures will range from 22°C to 34°C, depending on elevation—22°C to 28°C in high hills, 26°C to 30°C in mid-hills, and up to 34°C in lower regions. Minimum temperatures are expected to remain near normal, between 12°C and 24°C. Cooler conditions may persist in districts like Kullu and Lahaul-Spiti.

Week of August 15–21

Similar rainfall patterns are expected to continue, with scattered heavy rain episodes. Temperature trends will remain stable, though slightly below-normal maximum temperatures are likely in parts of Lahaul-Spiti, Mandi, Kangra, and Kullu districts.

Outlook for Late August

Rainfall is expected to remain broadly normal, with region-specific variations. Districts such as Kinnaur, Shimla, and Sirmaur may see below-normal precipitation, while Una, Kangra, Hamirpur, Bilaspur, and Solan are likely to receive above-average rainfall. Both maximum and minimum temperatures are forecast to stay close to seasonal norms.

Officials at the Meteorological Centre in Shimla have urged residents and local authorities to remain alert for sudden heavy downpours, which could disrupt road connectivity and trigger landslides—especially along vulnerable hillside routes. Past monsoon episodes have blocked key highways, including routes between Mandi and Kullu and near Banjar, underscoring the ongoing challenges in the region.

This advisory comes as Himachal Pradesh continues to face the dual pressures of sustaining its agriculture-dependent economy while managing the life and infrastructure risks posed by an active monsoon. Continued vigilance and preparedness remain crucial.

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Monsoon 2025: Himachal Pradesh Suffers 199 Casualties, Over ₹1,905.50 Cr in Damages

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SHIMLA | 7 August 2025 –Himachal Pradesh continues to deal with the impacts of the 2025 monsoon season, reporting extensive property damage, loss of lives, and widespread disruptions across the state. According to the official reports from the State Emergency Operations Centre (SEOC), the Department of Revenue, and the India Meteorological Department, from June 20 to August 6, 2025, heavy monsoon rains caused significant damage across multiple districts:

  • Casualties: 199 deaths due to landslides, flash floods, cloudbursts, drowning, lightning, electrocution, and accidents; 304 injuries reported.
  • Property Loss: Extensive damage to houses (both pucca and kaccha), shops, factories, labor sheds, animal shelters, and substantial crop losses in agriculture and horticulture.
  •  Public Infrastructure: Over ₹1,900 crore in damages to roads (including PWD), power supply, health, education, fisheries, rural and urban development, and animal husbandry.

Most affected districts include Mandi, Kangra, and Hamirpur, with severe crop and infrastructure losses.

Monsoon damages in himachal pradesh

 

Additionally, 91 deaths occurred due to monsoon-related road accidents.

Public Utilities and Infrastructure Disruptions

The SEOC report dated August 7, 2025, highlights ongoing disruptions:

  • Roads Blocked: About 493 major roads and 3 national highways (NH-305, NH-21, NH-05) remain blocked by landslides and floods.
  • Power Supply: Disruption of 1,120 distribution transformers (DTRs).
  •  Water Supply: 245 water schemes affected, threatening access to potable water for communities.

Key blockages include NH-21 between Mandi and Kullu and NH-305 near Banjar and Jhed.

Weather Forecast and Warnings

The India Meteorological Department’s forecast valid from August 7, 2025, includes:

  •  Isolated heavy rainfall expected throughout the week.
  •  Thunderstorms and lightning predicted in isolated areas.
  •  Minimum temperatures near normal or slightly below.
  •  Maximum temperatures showing a moderate increase.

The public is urged to remain vigilant due to the risks of further landslides and flash floods.

Himachal Pradesh remains vulnerable as the monsoon season continues, with thousands affected by damage, displacement, and disruption of essential services. Authorities are continuing with rescue and recovery operations and are urging residents to stay alert to the ongoing adverse weather. This situation highlights the pressing need for enhanced infrastructure and disaster management strategies to mitigate monsoon-related risks.

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